NanoImpactNet – QNano conference
"RNA-Loaded Nanoparticles Fight Cancer"
Up one levelIn first human trial, particles successfully reach cancer cells and silence the target gene.
A specialized nanoparticle filled with an RNA-based cancer therapy can successfully target human cancer cells and silence the target gene, according to results from an early clinical trial. The research, published today in the journal Nature, is the first to demonstrate this type of tissue targeting and gene-silencing in humans. Researchers haven't yet revealed the clinical effects of the treatment.
"It's a very exciting paper," says Phillip Sharp, an MIT professor who won the 1993 Nobel Prize in medicine for his work on RNA splicing. "It's a statement that we are in this stage in the field [where we're] beginning to use these particles to treat people."
